The relationship between early weight loss and weight loss at 1 year with naltrexone ER/bupropion ER combination therapy
نویسندگان
چکیده
منابع مشابه
Naltrexone/bupropion: an investigational combination for weight loss and maintenance.
Naltrexone/bupropion is an investigational combination for weight loss and maintenance in patients who are obese or have a BMI ≥ 27 kg/m(2) with comorbid diabetes, hypertension or hyperlipidemia. Pooled results from four phase 3 trials reveal placebo-subtracted mean weight loss of 4.7% (range 3.2-5.2%) with naltrexone/bupropion after 1 year (p < 0.001 vs. placebo in each trial). The placebo-sub...
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Objective Identifying early predictors of weight loss is key for developing personalized treatment. However, few individual factors have been identified that predict weight loss during intervention, other than early weight loss itself. Methods Women with overweight or obesity (n = 186, mean ± SD age 50.0 ± 10.6 years, body mass index 34.0 ± 4.2 kg m-2) participated in the Portion-Control Stra...
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OBJECTIVE To identify an early response criterion for predicting ≥5% weight loss with liraglutide 3.0 mg at week 56 and to compare efficacy outcomes in early responders (ERs) and early nonresponders (ENRs). METHODS Using pooled data from the SCALE Obesity and Prediabetes and SCALE Diabetes trials, weight loss of ≥4% at 16 weeks best predicted ≥5% weight loss after 56 weeks. Weight loss and ch...
متن کاملObesity & Weight Loss Therapy
Lessons Learned from a Community Based Lifestyle Intervention for Youth at Risk for Type 2 Diabetes Eva M Vivian1*, Lisa H Colbert2, Patrick L Remington3 1University of Wisconsin-Madison, School of Pharmacy, Madison, USA 2Departments of Kinesiology and Population Health Sciences, 2035 Gymnasium-Natatorium, 2000 Observatory Drive, Madison, USA 3UW School of Medicine and Public Health, Health Sci...
متن کاملObesity & Weight Loss Therapy
Type 2 Diabetes Mellitus (T2DM) is the most common and costly endocrine disease [1] which is associated with increased morbidity and premature death, especially from cardiovascular diseases, myocardial infarction and stroke [2]. The prevalence of T2DM has increased dramatically over the past two decades. According to the most recent survey, the number of people who are currently affected by thi...
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ژورنال
عنوان ژورنال: International Journal of Obesity
سال: 2016
ISSN: 0307-0565,1476-5497
DOI: 10.1038/ijo.2016.67